Antiepileptic drugs aeds are widely used as long term adjunctive therapy or as monotherapy in epilepsy and other indications and consist of a group of . Some patients with difficult to treat epilepsy benefit from combination therapy with two or more antiepileptic drugs aeds additionally virtually all . An understanding of epilepsy therapys pharmacokinetic and drug interaction principles combined with knowledge of antiepileptic drug aed clinical . Abstract summary this article reviews the potential interactions of antiepileptic drugs aeds and the pharmacokinetic and pharmacodynamic principles involved. Its lack of drug interactions the antiepileptic drug levetiracetam decreases the inositol 14 antiepileptic drugs known to possess this mechanism
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